|
KMID : 0882420120830020263
|
|
Korean Journal of Medicine
2012 Volume.83 No. 2 p.263 ~ p.267
|
|
|
Transformation of CD5-Negative Follicular Lymphoma into CD5-Positive Diffuse Large B-Cell Lymphoma: A Case Report
|
|
Kim Hyeong-Kug
Cho In-Sung
Lee Hye-Kyung
Choi Yong-Hun
Cho Seong-Min
Moon Hyun-Jin
Lee Jin-A
|
|
|
Abstract
|
|
|
|
Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype of aggressive lymphomas. Approximately 10% of DLBCL cases express CD5 as a surface antigen. CD5-positive DLBCL can occur as the de novo or secondary type. De novo CD5-positive DLBCL arises without previous lymphoproliferative disease, and secondary CD5-positive DLBCL may or may not manifest as Richter syndrome. The transformation of follicular lymphoma (FL) into DLBCL occurs in approximately one-third of all cases. The transformation of CD5-negative low-grade B-cell lymphoma to CD5-positive DLBCL is extremely rare. We report the clinical features of a rare case that presented with a transformation from CD5-negative FL to CD5-positive DLBL over 11 years. This is the second such case published in the English literature.
|
|
|
KEYWORD
|
|
|
Lymphoma, large B-cell, diffuse, Lymphoma, follicular, Cell transformation, neoplastic
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|